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. 2011 Jul;39(Web Server issue):W323-7.
doi: 10.1093/nar/gkr372. Epub 2011 May 23.

BioProfiling.de: analytical web portal for high-throughput cell biology

Alexey V Antonov  1
Affiliations

BioProfiling.de: analytical web portal for high-throughput cell biology

Alexey V Antonov. Nucleic Acids Res. 2011 Jul.

Abstract

BioProfiling.de provides a comprehensive analytical toolkit for the interpretation gene/protein lists. As input, BioProfiling.de accepts a gene/protein list. As output, in one submission, the gene list is analyzed by a collection of tools which employs advanced enrichment or network-based statistical frameworks. The gene list is profiled with respect to the most information available regarding gene function, protein interactions, pathway relationships, in silico predicted microRNA to gene associations, as well as, information collected by text mining. BioProfiling.de provides a user friendly dialog-driven web interface for several model organisms and supports most available gene identifiers. The web portal is freely available at http://www.BioProfiling.de/gene_list.

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Figures

Figure 1.
Figure 1.
According to the global PPI network, all 47 Bosutinib targets (rectangles), which can be mapped to the global PPI network can be connected into sub-network with maximum two missing genes (triangles) in between. The P-value estimated by Monte–Carlo simulation is < 0.005.
See this image and copyright information in PMC

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References

    1. Khatri P, Draghici S. Ontological analysis of gene expression data: current tools, limitations, and open problems. Bioinformatics. 2005;21:3587–3595. - PMC - PubMed
    1. Berger SI, Posner JM, Ma'ayan A. Genes2Networks: connecting lists of gene symbols using mammalian protein interactions databases. BMC Bioinformatics. 2007;8:372. - PMC - PubMed
    1. Draghici S, Khatri P, Tarca AL, Amin K, Done A, Voichita C, Georgescu C, Romero R. A systems biology approach for pathway level analysis. Genome Res. 2007;17:1537–1545. - PMC - PubMed
    1. Reimand J, Tooming L, Peterson H, Adler P, Vilo J. GraphWeb: mining heterogeneous biological networks for gene modules with functional significance. Nucleic Acids Res. 2008;36(Suppl. 2):W452–W459. - PMC - PubMed
    1. Subramanian A, Tamayo P, Mootha VK, Mukherjee S, Ebert BL, Gillette MA, Paulovich A, Pomeroy SL, Golub TR, Lander ES, et al. Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles. Proc. Natl Acad. Sci. USA. 2005;102:15545–15550. - PMC - PubMed

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