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Review
. 2011 May 27;11(7):489-95.
doi: 10.1038/nri2993.

The golden anniversary of the thymus

Jacques F A P Miller  1
Affiliations
Review

The golden anniversary of the thymus

Jacques F A P Miller. Nat Rev Immunol. .

Erratum in

  • Nat Rev Immunol. 2011 Dec;11(12):880

Abstract

The immunological function of the thymus was first documented 50 years ago by using neonatally thymectomized mice, while studying its role in virus-induced leukaemia. Since then, an enormous wealth of reports has helped to define the importance of this primary lymphoid organ. In this article, I summarize the key advances that have led to our current knowledge of the functions of the thymus and its T cells in immunity.

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