doi: 10.1016/0042-6822(90)90502-i.
New evidence for the precursor role of 14 S subunits in poliovirus morphogenesis
Affiliations
- PMID: 2162113
- DOI: 10.1016/0042-6822(90)90502-i
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New evidence for the precursor role of 14 S subunits in poliovirus morphogenesis
Virology.
1990 Jul.
Abstract
In poliovirus-infected HeLa cells incubated as 30 degrees, 14 S subunits are selectively labeled and no virions are assembled. When the temperature is subsequently shifted to 37 degrees, the radioactivity of the 14 S material is transferred mainly to virions, showing that 14 S subunits are virion precursors. When 14 S subunits synthesized at 30 degrees are incubated in vitro at 37 degrees, they assemble to empty capsids.
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