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Comment
. 2011 Jun 3;8(6):597-8.
doi: 10.1016/j.stem.2011.05.008.

Notch and basal cells take center stage during airway epithelial regeneration

Jeffrey A Whitsett  1 , Vladimir V Kalinichenko
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Free article
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Notch and basal cells take center stage during airway epithelial regeneration

Jeffrey A Whitsett et al. Cell Stem Cell. .
Free article

Abstract

Airway epithelium is maintained by basal cells, but the mechanisms responsible for repair are poorly characterized. In this issue of Cell Stem Cell, Rock et al. (2011) show that Notch signals regulate differentiation, but not self-renewal of basal cells after injury, and that this role appears conserved in mouse and human lung.

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