Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2011 Jun 3;8(6):604-5.
doi: 10.1016/j.stem.2011.05.007.

Epigenetic modifications in distinction: histone versus DNA methylation in ESCs

Kevin Huang  1 , Guoping Fan
Affiliations
Free article
Comment

Epigenetic modifications in distinction: histone versus DNA methylation in ESCs

Kevin Huang et al. Cell Stem Cell. .
Free article

Abstract

In this issue of Cell Stem Cell, Karimi et al. (2011) show that DNA methylation and histone H3 lysine 9 trimethylation (H3K9me3) have distinct genomic targets in mouse ESCs. In particular, loss of H3K9me3 leads to derepression of select endogenous retroviruses and subsequent ectopic transcription of adjacent genes.

PubMed Disclaimer

Comment on

LinkOut - more resources