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. 1969:1:67-76.

Hepatic Disorders in Renal Homograft Recipients

Israel Penn  1 , William Hammond, Peter Bell, Robert McGuire, Martin Hutt, Thomas Starzl
Affiliations

Hepatic Disorders in Renal Homograft Recipients

Israel Penn et al. Curr Top Surg Res. 1969.
No abstract available

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Figures

Fig. 1
Fig. 1
Time of onset of liver damage.
Fig. 2
Fig. 2
Serum glutamic-oxaloacetic transaminase (SGOT) and serum glutamic-pyruvic transaminase (SGPT) levels in renal homograft recipients. The SGOT was elevated in 59% of these patients, and the SGPT in 51 %. The normal values are less than 40 international units (IU) per liter. The levels shown here and in all the subsequent illustrations are the most abnormal observed in any given patient.
Fig. 3
Fig. 3
Total bilirubin was elevated above 1.0 mg/100 ml in 52 of the 143 patients studied. The normal values are less than 1.0 mg/100 ml.
Fig. 4
Fig. 4
Alkaline phosphatase was elevated in 65% of 132 patients after renal transplantation at some time in the postoperative course. The normal values are 14–38 IU.
Fig. 5
Fig. 5
Total serum proteins were markedly reduced in most patients. The values given are the lowest ever observed in any given case. (A) Total. (B) Albumin.
Fig. 6
Fig. 6
Prothrombin times were below 40% at some time in 22 of the 119 patients in which it was estimated.
Fig. 7
Fig. 7
Bromsulphalein (BSP) retention of greater than 6% after 45 minutes was observed in 31 of 39 patients in which this test was performed. The abnormal values usually improved with the passage of time.
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References

    1. Goodman LS, Gilman A. The Pharmacological Basis of Therapeutics. 3rd. Macmillan; New York: 1967. p. 572.p. 1145.p. 1210.p. 1211.p. 1212.p. 1242.p. 1294.
    1. Hamburger J, Crosnier J, Dormont J. Experience with 45 renal homotransplantations in man. Lancet. 1965;1:985. - PubMed
    1. Hamburger J, Crosnier J, Dormont J, Reveillaud RJ, Hors JH, Alsina J. Homotransplantation renale humaine. III. Complications extra-rénales. Presse Med. 1965;73:2911. - PubMed
    1. Hampers L, Prager D, Senior JR. Post-transfusion anicteric hepatitis. New Eng J Med. 1964;271:747. - PubMed
    1. Hill RB, Jr, Porter KA, Massion CG. Hepatic reaction to renal transplants modified by immunosuppressive therapy. Iron accumulation in hepatic injury. Arch Path (Chicago) 1966;81:71.

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