Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2011:4:359-71.
doi: 10.2147/IJGM.S19639. Epub 2011 May 17.

Standard operation procedures for conducting the on-the-road driving test, and measurement of the standard deviation of lateral position (SDLP)

Affiliations

Standard operation procedures for conducting the on-the-road driving test, and measurement of the standard deviation of lateral position (SDLP)

Joris C Verster et al. Int J Gen Med. 2011.

Abstract

This review discusses the methodology of the standardized on-the-road driving test and standard operation procedures to conduct the test and analyze the data. The on-the-road driving test has proven to be a sensitive and reliable method to examine driving ability after administration of central nervous system (CNS) drugs. The test is performed on a public highway in normal traffic. Subjects are instructed to drive with a steady lateral position and constant speed. Its primary parameter, the standard deviation of lateral position (SDLP), ie, an index of 'weaving', is a stable measure of driving performance with high test-retest reliability. SDLP differences from placebo are dose-dependent, and do not depend on the subject's baseline driving skills (placebo SDLP). It is important that standard operation procedures are applied to conduct the test and analyze the data in order to allow comparisons between studies from different sites.

Keywords: SDLP; driving test; highway; methodology; on-the-road.

PubMed Disclaimer

Figures

Figure 1
Figure 1
The standard deviation of lateral position (SDLP).
Figure 2
Figure 2
One of the instrumented cars of Utrecht University.
Figure 3
Figure 3
Schematic representation of the on-the-road driving test.
Figure 4
Figure 4
Examples of lateral position and speed changes over distance traveled. Adapted with permisison from Volkerts ER, de Vries G, Meijer T, et al. Driving performance the day after use of loprazolam, flunitrazepam and placebo. VSC, Report VK 83-04, Traffic Research Centre, Groningen, The Netherlands, 1984.
Figure 5
Figure 5
Standard operation procedures to edit the raw data of the driving test. The top figure shows the mean lateral position (MLP) of the car. The bottom figure shows the mean speed (MS) of the car. Standard operation procedures: A) Start of the test: data is deleted until the subject drives 95 km/h in gear number 5. B) An overtaking maneuver: data is deleted from the start of accelerating to overtake, or moving to the left lane, until the car is returned completely back on the right lane and its speed is returned to 95 km/hour. C) Attempt to overtake: data is deleted from the first attempt to overtake. D) Between two overtaking maneuvers: data is deleted when the distance between the two maneuvers is at less than 600 meters. E) Out of the detection range: data is deleted. F) Collisions, off road crashes, other events requiring stopping or slowing speed: data is deleted from the moment of the crash until the car drives 95 km/hour in gear number 5. Cut-off points for editing are indicated by |.
Figure 6
Figure 6
SDLP values obtained after administration of placebo. Data from references , –.
Figure 7
Figure 7
Test–retest reliability of SDLP measurement. Data from n = 98 healthy volunteers (data from references , –18). Note: Driving tests were performed in the morning or afternoon following bedtime administration of placebo (9–10 hours and 16–17 hours after intake).
Figure 8
Figure 8
SDLP values and weather conditions. Data from 174 driving tests of healthy volunteers who received placebo treatment (Data from references –23, 25).
Figure 9
Figure 9
SDLP values over distance traveled. The left Figure shows SDLP values calculated for 10 km segments of 214 subjects who drove after receiving placebo (Data from references 11, 12, 17, 18, 22, 23). The right panel shows SDLP values obtained after 1, 4, and 8 hours of continuous driving (Data from reference 27).
Figure 10
Figure 10
The impact of mean lateral position changes on SDLP. Abbreviations: MLP, mean lateral position; SDLP, standard deviation of lateral position.
Figure 11
Figure 11
Subjective assessments completed after the driving test. Subjects indicate their perceived driving quality (left figure) and perceived effort (right figure) by placing an ‘X’ at the vertical line.
Figure 12
Figure 12
SDLP differences from placebo (cm) after administration of flurazepam (30 mg). When absolute placebo SDLP values increase, the difference from placebo does not (r = 0.16, n.s.). Data from reference , .

References

    1. Vermeeren A, de Gier JJ, O’Hanlon JF. Methodological guidelines for experimental drugs affecting driving performance: an international expert survey. Maastricht: Institute for Human Psychopharmacology, University of Limburg, The Netherlands; 1993.
    1. O’Hanlon JF, Haak TW, Blaauw GJ, Riemersma JB. Diazepam impairs lateral position control in highway driving. Science. 1982;217(4554):79–81. - PubMed
    1. O’Hanlon JF. Driving under the influence of drugs: rationale for, and application of, a new test. Br J Clin Pharmacol. 1984;18(Suppl 1):121S–129S. - PMC - PubMed
    1. O’Hanlon JF. Are actual driving tests necessary for evaluating drug safety? Int Clin Psychopharmacol. 1988;3(Suppl 1):81–85. - PubMed
    1. Penning R, Veldstra J, Daamen AP, Olivier B, Verster JC. Drugs of abuse, driving and traffic safety. Curr Drug Abuse Rev. 2010;3(1):23–32. - PubMed