Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2011 Jun;86(6):561-83.
doi: 10.4065/mcp.2011.0203.

Antiparasitic therapy

Shanthi Kappagoda  1 , Upinder Singh, Brian G Blackburn
Affiliations
Review

Antiparasitic therapy

Shanthi Kappagoda et al. Mayo Clin Proc. 2011 Jun.

Abstract

Parasitic diseases affect more than 2 billion people globally and cause substantial morbidity and mortality, particularly among the world's poorest people. This overview focuses on the treatment of the major protozoan and helminth infections in humans. Recent developments in antiparasitic therapy include the expansion of artemisinin-based therapies for malaria, new drugs for soil-transmitted helminths and intestinal protozoa, expansion of the indications for antiparasitic drug treatment in patients with Chagas disease, and the use of combination therapy for leishmaniasis and human African trypanosomiasis.

PubMed Disclaimer

References

    1. Centers for Disease Control and Prevention (CDC) Guidelines for treatment of malaria in the United States. http://www.cdc.gov/malaria/resources/pdf/treatmenttable.pdf Accessed April 29, 2011
    1. Maude RJ, Plewes K, Faiz MA, et al. Does artesunate prolong the electrocardiograph QT interval in patients with severe malaria? Am J Trop Med Hyg. 2009;80:126-132 - PMC - PubMed
    1. Dondorp A, Nosten F, Stepniewska K, Day N, White N. Artesunate versus quinine for treatment of severe falciparum malaria: a randomised trial. Lancet. 2005;366:717-725 - PubMed
    1. Dondorp AM, Fanello CI, Hendriksen IC, et al. Artesunate versus quinine in the treatment of severe falciparum malaria in African children (AQUAMAT): an open-label, randomised trial. Lancet. 2010;376:1647-1657 - PMC - PubMed
    1. Centers for Disease Control and Prevention (CDC) Notice to readers: new medication for severe malaria available under an investigational new drug protocol. Morb Mortal Wkly Rep. 2007;56(30):769-770 http://www.cdc.gov/Mmwr/preview/mmwrhtml/mm5630a5.htm Accessed April 29, 2011

Publication types

MeSH terms