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Comparative Study
. 2011 Aug;49(8):3029-32.
doi: 10.1128/JCM.00422-11. Epub 2011 Jun 1.

Evaluation of a new DNA test for detection of carcinogenic human papillomavirus

Philip E Castle  1 , Erin C Gutierrez, Sharon V Leitch, Courtney E Maus, Ray A McMillian, William A Nussbaumer, Laurence M Vaughan, Cosette M Wheeler, Patti E Gravitt, Mark Schiffman
Affiliations
Comparative Study

Evaluation of a new DNA test for detection of carcinogenic human papillomavirus

Philip E Castle et al. J Clin Microbiol. 2011 Aug.

Abstract

Using archived specimens, we evaluated a new automated real-time PCR assay (BD Diagnostics) that detects all carcinogenic human papillomaviruses (HPV) and provides HPV genotyping for seven of them, including HPV16 and HPV18, the two most carcinogenic HPV genotypes. We found comparable results with Hybrid Capture 2 (HC2) for detection of carcinogenic HPV (n = 473) and with Linear Array and Line Blot Assay (n = 371) for detection of individual HPV genotypes.

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References

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