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Comment
. 2011 Jun;13(6):636-7.
doi: 10.1038/ncb0611-636.

Wnt signalling escapes to cilia

Rieko Ajima, Hiroshi Hamada
Comment

Wnt signalling escapes to cilia

Rieko Ajima et al. Nat Cell Biol. 2011 Jun.

Abstract

The primary cilium is proposed to restrain the level of canonical Wnt signalling, but it was unknown how the cilium achieves this. β-catenin, a component of the canonical Wnt signalling pathway, is now shown to be sequestered to the cilium by the Wnt signalling modulator Jouberin (Jbn) to restrain Wnt responses.

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References

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