The relative proportion of H1(0) and A24 is reversed in oligodendrocytes during rat brain development
- PMID: 2163755
- PMCID: PMC11567209
- DOI: 10.1007/BF00734579
The relative proportion of H1(0) and A24 is reversed in oligodendrocytes during rat brain development
Abstract
1. The histone complement of oligodendrocyte chromatin at different stages of brain development was studied after acid extraction of nuclei. 2. HCl-soluble proteins were analyzed by different electrophoretic techniques. 3. Our results show an increase in the concentration of histone H1(0) with differentiation. 4. The increase in H1(0) is accompanied by a concomitant decrease in the total amount of the ubiquitinated form of histone H2A (A24).
Similar articles
-
Qualitative differences in nuclear proteins correlate with neuronal terminal differentiation.Cell Mol Neurobiol. 1992 Feb;12(1):33-43. doi: 10.1007/BF00711637. Cell Mol Neurobiol. 1992. PMID: 1571953 Free PMC article.
-
Histone H1o in developing rat brain cells.Differentiation. 1984;28(2):191-4. doi: 10.1111/j.1432-0436.1984.tb00283.x. Differentiation. 1984. PMID: 6526167
-
Histone 1 is proximal to histone 2A and to A24.Proc Natl Acad Sci U S A. 1979 May;76(5):2190-4. doi: 10.1073/pnas.76.5.2190. Proc Natl Acad Sci U S A. 1979. PMID: 287057 Free PMC article.
-
Keeping the ageing brain wired: a role for purine signalling in regulating cellular metabolism in oligodendrocyte progenitors.Pflugers Arch. 2021 May;473(5):775-783. doi: 10.1007/s00424-021-02544-z. Epub 2021 Mar 13. Pflugers Arch. 2021. PMID: 33712969 Free PMC article. Review.
-
Relationship of H1(0) histone to differentiation and cancer.Cancer Biochem Biophys. 1987 Sep;9(3):199-209. Cancer Biochem Biophys. 1987. PMID: 3325165 Review.
Cited by
-
H1(0) and H3.3B mRNA levels in developing rat brain.Neurochem Res. 1994 Dec;19(12):1531-7. doi: 10.1007/BF00969002. Neurochem Res. 1994. PMID: 7877725
-
The dynamic properties of neuronal chromatin are modulated by triiodothyronine.Neurochem Res. 1992 Nov;17(11):1049-55. doi: 10.1007/BF00967280. Neurochem Res. 1992. PMID: 1461355
-
H1.0 Linker Histone as an Epigenetic Regulator of Cell Proliferation and Differentiation.Genes (Basel). 2018 Jun 20;9(6):310. doi: 10.3390/genes9060310. Genes (Basel). 2018. PMID: 29925815 Free PMC article. Review.
-
Qualitative differences in nuclear proteins correlate with neuronal terminal differentiation.Cell Mol Neurobiol. 1992 Feb;12(1):33-43. doi: 10.1007/BF00711637. Cell Mol Neurobiol. 1992. PMID: 1571953 Free PMC article.
-
Effects of triiodothyronine (T3) on differentiation of rat cortical neurons in primary cultures.Cytotechnology. 1991 Feb;5(Suppl 1):168-71. doi: 10.1007/BF00736840. Cytotechnology. 1991. PMID: 22358986
References
-
- Brown, I. R. (1978). Postnatal appearance of short DNA repeat length in neurons of the cerebral cortex.Biochem. Biophys. Res. Commun.84285–292. - PubMed
-
- Cole, R. D. (1984). A minireview of microheterogeneity in H1 histone and its possible significance.Anal. Biochem.13624–30. - PubMed
-
- Di Liegro, I., Salemi, G., and Cestelli, A. (1985). A low repeat length in oligodendrocyte chromatin.J. Neurochem.451006–1012. - PubMed
-
- Goldknopf, I. L., Taylor, C. W., Baum, R. M., Yeoman, L. C., Olson, M. O. J., Prestayko, A. W., and Busch, H. (1975). Isolation and characterization of protein A24, a “histone-like” non-histone chromosomal protein.J. Biol. Chem.2507182–7187. - PubMed
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical