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. 1990 Jun;10(2):267-74.
doi: 10.1007/BF00734579.

The relative proportion of H1(0) and A24 is reversed in oligodendrocytes during rat brain development

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The relative proportion of H1(0) and A24 is reversed in oligodendrocytes during rat brain development

I Di Liegro et al. Cell Mol Neurobiol. 1990 Jun.

Abstract

1. The histone complement of oligodendrocyte chromatin at different stages of brain development was studied after acid extraction of nuclei. 2. HCl-soluble proteins were analyzed by different electrophoretic techniques. 3. Our results show an increase in the concentration of histone H1(0) with differentiation. 4. The increase in H1(0) is accompanied by a concomitant decrease in the total amount of the ubiquitinated form of histone H2A (A24).

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