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. 2011 Aug;44(12):1021-4.
doi: 10.1016/j.clinbiochem.2011.05.017. Epub 2011 May 24.

High sensitivity troponin T concentrations in patients undergoing noncardiac surgery: a prospective cohort study

Peter A Kavsak  1 , Mike Walsh, Sadeesh Srinathan, Laurel Thorlacius, Giovanna Lurati Buse, Fernando Botto, Shirley Pettit, Matthew J McQueen, Stephen A Hill, Sabu Thomas, Marko Mrkobrada, Pablo Alonso-Coello, Otavio Berwanger, Bruce M Biccard, George Cembrowski, Matthew T V Chan, Clara K Chow, Angeles de Miguel, Mercedes Garcia, Michelle M Graham, Michael J Jacka, J H Kueh, Stephen C H Li, Lydia C W Lit, Cecília Martínez-Brú, Prebashini Naidoo, Peter Nagele, Rupert M Pearse, Reitze N Rodseth, Daniel I Sessler, Alben Sigamani, Wojciech Szczeklik, Maria Tiboni, Juan Carlos Villar, C Y Wang, Denis Xavier, P J Devereaux
Affiliations

High sensitivity troponin T concentrations in patients undergoing noncardiac surgery: a prospective cohort study

Peter A Kavsak et al. Clin Biochem. 2011 Aug.

Abstract

Objectives: To determine the proportion of noncardiac surgery patients exceeding the published 99th percentile or change criteria with the high sensitivity Troponin T (hs-TnT) assay.

Design and methods: We measured hs-TnT preoperatively and postoperatively on days 1, 2 and 3 in 325 adults.

Results: Postoperatively 45% (95% CI: 39-50%) of patients had hs-TnT≥14ng/L and 22% (95% CI:17-26%) had an elevation (≥14ng/L) and change (>85%) in hs-TnT.

Conclusion: Further research is needed to inform the optimal hs-TnT threshold and change in this setting.

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