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. 1978;34(5-6):275-7.
doi: 10.1159/000241140.

The binding of 125I-TSH to thyroid cell receptors previously deformed (in neonatal age) by gonadotropin treatment

G Csaba, S U Nagy

The binding of 125I-TSH to thyroid cell receptors previously deformed (in neonatal age) by gonadotropin treatment

G Csaba et al. Biol Neonate. 1978.

Abstract

Single gonadotropin treatment of newborn rats caused a 63-71% decrease of TSH-binding on isolated thyroid cells prepared from thyroid glands of both 6- and 13-month-old animals. This fact points out that: (1) in newborn animals the hormone receptors are still plastic and deformable and (2) the damaging effect of the analogous hormone manifests itself at the receptor level.

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