Comment
doi: 10.1016/j.str.2011.05.007.
Recombining DNA by protein swivels
Affiliations
- PMID: 21645847
- DOI: 10.1016/j.str.2011.05.007
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Comment
Recombining DNA by protein swivels
Structure.
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Abstract
Two new reports on serine recombinases, one of a crystal snapshot in an alternate rotational conformer poised for DNA cleavage (Keenholtz et al., 2011), and a second employing single-DNA molecule approaches (Bai et al., 2011), provide strong support for the subunit rotation model for exchanging DNA strands.
Copyright © 2011 Elsevier Ltd. All rights reserved.
Comment on
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Single-molecule analysis reveals the molecular bearing mechanism of DNA strand exchange by a serine recombinase.Proc Natl Acad Sci U S A. 2011 May 3;108(18):7419-24. doi: 10.1073/pnas.1018436108. Epub 2011 Apr 18. Proc Natl Acad Sci U S A. 2011. PMID: 21502527 Free PMC article.
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Structural basis for catalytic activation of a serine recombinase.Structure. 2011 Jun 8;19(6):799-809. doi: 10.1016/j.str.2011.03.017. Structure. 2011. PMID: 21645851 Free PMC article.