Purification and characterization of a calicivirus as the causative agent of a lethal hemorrhagic disease in rabbits
- PMID: 2164609
- PMCID: PMC249702
- DOI: 10.1128/JVI.64.8.4013-4015.1990
Purification and characterization of a calicivirus as the causative agent of a lethal hemorrhagic disease in rabbits
Abstract
The causative viral agent of a lethal rabbit hemorrhagic disease has been purified and characterized. In negative-stained preparations, the virions were icosahedral, measured 27 to 35 nm in diameter, were without an envelope, and showed 10 peripheral cup-shaped depressions. The major structural protein was 60 kilodaltons, which constitutes a unique characteristic of the Caliciviridae.
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