Comment on

• Cop1 constitutively regulates c-Jun protein stability and functions as a tumor suppressor in mice.

  Migliorini D, Bogaerts S, Defever D, Vyas R, Denecker G, Radaelli E, Zwolinska A, Depaepe V, Hochepied T, Skarnes WC, Marine JC. Migliorini D, et al. J Clin Invest. 2011 Apr;121(4):1329-43. doi: 10.1172/JCI45784. Epub 2011 Mar 14. J Clin Invest. 2011. PMID: 21403399 Free PMC article.
• COP1 is a tumour suppressor that causes degradation of ETS transcription factors.

  Vitari AC, Leong KG, Newton K, Yee C, O'Rourke K, Liu J, Phu L, Vij R, Ferrando R, Couto SS, Mohan S, Pandita A, Hongo JA, Arnott D, Wertz IE, Gao WQ, French DM, Dixit VM. Vitari AC, et al. Nature. 2011 May 15;474(7351):403-6. doi: 10.1038/nature10005. Nature. 2011. PMID: 21572435