Multiple personalities in the ventral tegmental area
- PMID: 21658574
- PMCID: PMC4910874
- DOI: 10.1016/j.neuron.2011.05.024
Multiple personalities in the ventral tegmental area
Abstract
A small number of ventral tegmental area dopamine neurons engage in numerous and apparently contradictory functions--how can this be? A clue is provided by Lammel and colleagues in this issue of Neuron: some VTA dopamine neurons display synaptic plasticity in response to cocaine, and others in response to pain, and these populations are distinguished by their axonal projections and Ih.
Copyright © 2011 Elsevier Inc. All rights reserved.
Comment on
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Projection-specific modulation of dopamine neuron synapses by aversive and rewarding stimuli.Neuron. 2011 Jun 9;70(5):855-62. doi: 10.1016/j.neuron.2011.03.025. Neuron. 2011. PMID: 21658580 Free PMC article.
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