Prostate cancer: molecular insights into bone metastasis

Comment

Sarah Payton. Nat Rev Urol. 2011.

. 2011 Jun 10;8(6):291.

doi: 10.1038/nrurol.2011.71.

No abstract available

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Human prostate cancer metastases target the hematopoietic stem cell niche to establish footholds in mouse bone marrow.
Shiozawa Y, Pedersen EA, Havens AM, Jung Y, Mishra A, Joseph J, Kim JK, Patel LR, Ying C, Ziegler AM, Pienta MJ, Song J, Wang J, Loberg RD, Krebsbach PH, Pienta KJ, Taichman RS. Shiozawa Y, et al. J Clin Invest. 2011 Apr;121(4):1298-312. doi: 10.1172/JCI43414. Epub 2011 Mar 23. J Clin Invest. 2011. PMID: 21436587 Free PMC article.
FOXO1 inhibits Runx2 transcriptional activity and prostate cancer cell migration and invasion.
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