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. 2011:2011:276734.
doi: 10.4061/2011/276734. Epub 2011 May 25.

The Link between Cognitive Measures and ADLs and IADL Functioning in Mild Alzheimer's: What Has Gender Got to Do with It?

James R Hall  1 , Hoa T Vo, Leigh A Johnson, Robert C Barber, S E O'Bryant
Affiliations

The Link between Cognitive Measures and ADLs and IADL Functioning in Mild Alzheimer's: What Has Gender Got to Do with It?

James R Hall et al. Int J Alzheimers Dis. 2011.

Abstract

Objectives. To investigate the link between neurocognitive measures and various aspects of daily living (ADL and IADL) in women and men with mild Alzheimer's disease (AD). Methods. Participants were 202 AD patients (91 male, 111 female) with CDR global scores of ≤1. ADLs and IADLs ratings were obtained from caregivers. Cognitive domains were assessed with neuropsychological testing. Results. Memory and executive functioning were related to IADL scores. Executive functioning was linked to total ADL. Comparisons stratified on gender found attention predicted total ADL score in both men and women. Attention predicted bathing and eating ability in women only. Language predicted IADL functions in men (food preparation) and women (driving). Conclusions. Associations between ADLs/IADLs and memory, learning, executive functioning, and language suggest that even in patients with mild AD, basic ADLs require complex cognitive processes. Gender differences in the domains of learning and memory area were found.

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Figures

Figure 1
Figure 1
Predicting ADL and IADLs in men and women with AD.
See this image and copyright information in PMC

References

    1. Beck CK, Frank LB. Assessing functioning and self-care abilities in Alzheimer disease research. Alzheimer Disease & Associated Disorders. 1997;11(6):73–80. - PubMed
    1. Busse A, Bischkopf J, Riedel-Heller SG, Angermeyer MC. Subclassifications for mild cognitive impairment: prevalence and predictive validity. Psychological Medicine. 2003;33(6):1029–1038. - PubMed
    1. Tekin S, Fairbanks LA, O’Connor S, Rosenberg S, Cummings JL. Activities of daily living in Alzheimer’s disease: neuropsychiatric, cognitive, and medical illness influences. The American Journal of Geriatric Psychiatry. 2001;9(1):81–86. - PubMed
    1. Gauthier S, Gelinas I, Gauthier L. Functional disability in Alzheimer’s disease. International Psychogeriatrics. 1997;9(1):163–165. - PubMed
    1. Ernst RL, Hay JW. The US economic and social costs of Alzheimer’s disease revisited. American Journal of Public Health. 1994;84(8):1261–1264. - PMC - PubMed

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