Viperin turns coat in cytomegalovirus infection
- PMID: 21664572
- DOI: 10.1016/j.devcel.2011.05.016
Viperin turns coat in cytomegalovirus infection
Abstract
Cytomegalovirus infection is associated with cytoskeletal alterations and cell swelling (cytomegaly), which have been attributed to the viral mitochondria-localized inhibitor of apoptosis (vMIA) protein. In a recent issue of Science, Seo et al. (2011) showed that the antiviral host protein viperin is co-opted to function with vMIA for facilitating infection.
Copyright © 2011 Elsevier Inc. All rights reserved.
Comment on
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Human cytomegalovirus directly induces the antiviral protein viperin to enhance infectivity.Science. 2011 May 27;332(6033):1093-7. doi: 10.1126/science.1202007. Epub 2011 Apr 28. Science. 2011. PMID: 21527675
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