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Comment
. 2011 Jun 14;19(6):695-7.
doi: 10.1016/j.ccr.2011.05.021.

ROCK-driven actomyosin contractility induces tissue stiffness and tumor growth

Sandra Kümper  1 , Christopher J Marshall
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ROCK-driven actomyosin contractility induces tissue stiffness and tumor growth

Sandra Kümper et al. Cancer Cell. .
Free article

Abstract

The tumor environment consists of tumor-associated cells, such as macrophages, fibroblasts, and extracellular matrix, and has an important impact on tumor progression. In this issue of Cancer Cell, Samuel et al. show that ROCK-driven actomyosin contractility increases tissue stiffness affecting epidermal homeostasis, as well as tumor growth and progression.

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