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Comment
. 2011 Jun 14;19(6):697-9.
doi: 10.1016/j.ccr.2011.05.022.

Turning reciprocal feedback regulation into combination therapy

Timothy C Thompson  1
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Free article
Comment

Turning reciprocal feedback regulation into combination therapy

Timothy C Thompson. Cancer Cell. .
Free article

Erratum in

  • Cancer Cell. 2011 Jul 12;20(1):132

Abstract

Two recent Cancer Cell articles report the discovery of reciprocal feedback regulation between androgenic and PTEN loss/PI3K-AKT signaling in prostate cancer. Both studies link endocrine regulation with a common oncogenic pathway, which led to the development of a combination therapeutic approach with immediate application in prostate cancer.

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