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Randomized Controlled Trial
. 2011 Aug;14(4):317-24.
doi: 10.1007/s00737-011-0222-6. Epub 2011 Jun 12.

Problem-solving education to prevent depression among low-income mothers of preterm infants: a randomized controlled pilot trial

Affiliations
Randomized Controlled Trial

Problem-solving education to prevent depression among low-income mothers of preterm infants: a randomized controlled pilot trial

Michael Silverstein et al. Arch Womens Ment Health. 2011 Aug.

Abstract

We sought to assess the feasibility and document key study processes of a problem-solving intervention to prevent depression among low-income mothers of preterm infants. A randomized controlled pilot trial (n = 50) of problem-solving education (PSE) was conducted. We assessed intervention provider training and fidelity; recruitment and retention of subjects; intervention acceptability; and investigators' ability to conduct monthly outcome assessments, from which we could obtain empirical estimates of depression symptoms, stress, and functioning over 6 months. Four of four bachelor-level providers were able to deliver PSE appropriately with standardized subjects within 4 weeks of training. Of 12 randomly audited PSE sessions with actual subjects, all met treatment fidelity criteria. Nineteen of 25 PSE subjects (76%) received full four-session courses; no subjects reported negative experiences with PSE. Eighty-eight percent of scheduled follow-up assessments were completed. Forty-four percent of control group mothers experienced an episode of moderately severe depression symptoms over the follow-up period, compared to 24% of PSE mothers. Control mothers experienced an average 1.19 symptomatic episodes over the 6 months of follow-up, compared to 0.52 among PSE mothers. PSE appears feasible and may be a promising strategy to prevent depression among mothers of preterm infants.

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Figures

Fig. 1
Fig. 1
Flow of subjects through randomized trial
Fig. 2
Fig. 2
Survival analysis depicting time to symptomatic episode. Slashes above the survival plot depict the density of PSE sessions delivered over time

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