Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2011;15(3):162.
doi: 10.1186/cc10234. Epub 2011 Jun 1.

Is faster still better in therapeutic hypothermia?

Affiliations
Comment

Is faster still better in therapeutic hypothermia?

Daniel Howes et al. Crit Care. 2011.

Abstract

The rapid institution of therapeutic hypothermia after cardiac arrest has become an accepted practice. In the previous issue of Critical Care, Haugk and colleagues present a retrospective analysis of 13 years of experience with therapeutic hypothermia at their center that suggests an association between rate of cooling and less favorable neurological outcomes. The association most likely reflects easier cooling in patients more severely brain injured by their initial cardiac arrest, and should not lead clinicians to abandon or slow their efforts to achieve post-resuscitative cooling.

PubMed Disclaimer

Comment on

References

    1. Haugk M, Testori C, Sterz F, Uranitsch M, Holzer M, Behringer W, Herkner H. Relationship between time to target temperature and outcome in patients treated with therapeutic hypothermia after cardiac arrest. Crit Care. 2011;15:R101. doi: 10.1186/cc10116. - DOI - PMC - PubMed
    1. Neumar RW, Adrie C, Aibiki M, Berg RA, Bottiger BW, Clark RSB, Geocadin RG, Jauch EC, Kern KB, Laurent I, Longstreth WT, Merchant RM, Morrison LJ, Madkarni V, Peberdy MA, Rivers EP, Rodriguez-Nunez A, Sellke FW, Spaulding C, Sunde K, Vanden Hoek T. Postcardiac arrest syndrome: epidemiology, pathophysiology, treatment, and prognostication A scientific statement from the international liaison committee on resuscitation; the American heart association emergency cardiovascular care committee; the council on cardiovascular surgery and anesthesia, the council on cardiopulmonary, perioperative and critical care, the council on clinical cardiology; the council on stroke. Resuscitation. 2008;79:350–379. doi: 10.1016/j.resuscitation.2008.09.017. - DOI - PubMed
    1. White C, Marcheselli VL, Janata A, Schratter A, Weihs W, Bayegan K, Milani RV, Bazan NG. Lipid mediators as novel biomarkers and surrogate indicators of neurologic recovery after cardiac arrest in a hypothermic swine model. Circulation. 2006;114:II 1203.
    1. Kazutoshi K, Safar P, Radovsky A, Tisherman SA, Stezoski SW, Alexander H. Delay in cooling negates the beneficial effect of mild resuscitative cerebral hypothermia after cardiac arrest in dogs: a prospective, randomized study. Crit Care Med. 1993;21:1348–1358. doi: 10.1097/00003246-199309000-00019. - DOI - PubMed
    1. Noguchi K, Matsumoto N, Shiozaki T, Tasaki O, Ogura H, Kuwagata Y, Sugimoto H, Seiyama A. Effects of timing and duration of hypothermia on survival in an experimental gerbil model of global ischemia. Resuscitation. 2011;82:481–486. doi: 10.1016/j.resuscitation.2010.09.477. - DOI - PubMed