Coexistence of low secretion of gonadotropins and ACTH in a patient with gonadal dysgenesis and pituitary tumor

Abstract

A 56-year-old woman with gonadal dysgenesis and pituitary adenoma is described. The unusual feature in this patient was the coexistence of a low gonadotropin level with secondary ACTH deficiency rather than the high gonadotropin level usually found in gonadal dysgenesis. Secretion of the other pituitary hormones was normal. Several hypotheses for such an unusual combination are presented.