[Antiviral drugs]

Abstract

It is 50 years since the first antiviral drug--JUDR for the local herpes keratitis was introduced and over 25 years since HIV/AIDS was isolated and the Noble Prize in Medicine and Physiology was given to its discovers. Now, there are 50 antiviral drugs, in which 25 are for HIV, the others are for herpes virus, shingles, cytomegalovirus, hepatitis virus and influenza A virus. Drugs for hemorrhagic fever Ebola and Marbourg as well as Denga fever are under way In the paper the current knowledge on chemotherapy and prophylaxis is presented in the following viral infections: HIV, HBV, HCV, CMV, HSV, shingles and other. The paper also demonstrates different groups of antiviral drugs, their use and efficacy. Mechanisms of infections and activity of antiviral drugs are analyzed.