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Comparative Study
. 1990 Aug 16;170(3):1074-81.
doi: 10.1016/0006-291x(90)90502-e.

Alternative splicing of mouse brain 2',3'-cyclic-nucleotide 3'-phosphodiesterase mRNA

T Kurihara  1 , K Monoh, K Sakimura, Y Takahashi
Affiliations
Comparative Study

Alternative splicing of mouse brain 2',3'-cyclic-nucleotide 3'-phosphodiesterase mRNA

T Kurihara et al. Biochem Biophys Res Commun. .

Abstract

A second cDNA for mouse brain 2',3'-cyclic-nucleotide 3'-phosphodiesterase (cDNAII) encoding 420 amino acids was isolated. The only difference from the cDNA obtained previously (cDNAI), which encodes 400 amino acids, was the 5'-end 53 bp. Comparison of the sequence of the mouse gene with the sequence of cDNAII indicates alternative splicing within exon 1. The 5'-end sequence of cDNAII was found in a region of the gene upstream of exon 1 and a second transcription initiation site was identified.

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