Fortification of corn masa flour with folic acid in the United States
- PMID: 21680940
- PMCID: PMC3134499
- DOI: 10.2105/AJPH.2011.300135
Fortification of corn masa flour with folic acid in the United States
Abstract
Food fortification is an effective public health tool for addressing micronutrient deficiencies. The mandatory fortification of enriched cereal grains (e.g., wheat flour) with folic acid, which began in the United States in 1998, is an example of a successful intervention that significantly reduced the rate of neural tube defects (NTDs). However, despite the drop in NTD rates across all racial/ethnic groups after fortification, Hispanics continue to have the highest rates of this condition. One possible way to reduce this disparity is to fortify corn masa flour to increase the overall intake of folic acid in Hispanic women. We present the available evidence in favor of this approach, address possible safety issues, and outline next steps in the fortification of corn masa flour with folic acid in the United States.
Figures
References
-
- Centers for Disease Control and Prevention Spina bifida and anencephaly before and after folic acid mandate—United States, 1995–1996 and 1999–2000. MMWR Morb Mortal Wkly Rep. 2004;53(17):362–365 - PubMed
-
- Botto LD, Moore CA, Khoury MJ, Erickson JD. Neural-tube defects. N Engl J Med. 1999;341(20):1509–1519 - PubMed
-
- Williams LJ, Rasmussen SA, Flores A, Kirby RS, Edmonds LD. Decline in the prevalence of spina bifida and anencephaly by race/ethnicity: 1995–2002. Pediatrics. 2005;116(3):580–586 - PubMed
-
- Sadler TW. Embryology of neural tube development. Am J Med Genet C Semin Med Genet. 2005;135C(1):2–8 - PubMed
-
- Finer LB, Henshaw SK. Disparities in rates of unintended pregnancy in the United States, 1994 and 2001. Perspect Sex Reprod Health. 2006;38(2):90–96 - PubMed
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical
