Genome-wide mapping of the sixth base

Affiliations

Comment

Dinh Diep et al. Genome Biol. 2011.

. 2011 Jun 20;12(6):116.

doi: 10.1186/gb-2011-12-6-116. Epub 2011 Jun 20.

¹ Department of Bioengineering, University of California at San Diego, 9500 Gilman Drive, MC0412, La Jolla, CA 92093-0412, USA.

Abstract

Mapping of 5-hydroxylmethylcytosine in mammalian genomes has unveiled its unique role in the epigenetic regulation of gene expression.

5-Hydroxymethylcytosine is associated with enhancers and gene bodies in human embryonic stem cells.
Stroud H, Feng S, Morey Kinney S, Pradhan S, Jacobsen SE. Stroud H, et al. Genome Biol. 2011 Jun 20;12(6):R54. doi: 10.1186/gb-2011-12-6-r54. Genome Biol. 2011. PMID: 21689397 Free PMC article.

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