Genome of multidrug-resistant uropathogenic Escherichia coli strain NA114 from India
- PMID: 21685291
- PMCID: PMC3147708
- DOI: 10.1128/JB.05413-11
Genome of multidrug-resistant uropathogenic Escherichia coli strain NA114 from India
Abstract
Uropathogenic Escherichia coli (UPEC) causes serious infections in people at risk and has a significant environmental prevalence due to contamination by human and animal excreta. In developing countries, UPEC assumes importance in certain dwellings because of poor community/personal hygiene and exposure to contaminated water or soil. We report the complete genome sequence of E. coli strain NA114 from India, a UPEC strain with a multidrug resistance phenotype and the capacity to produce extended-spectrum beta-lactamase. The genome sequence and comparative genomics emanating from it will be significant in under-standing the genetic makeup of diverse UPEC strains and in boosting the development of new diagnostics/vaccines.
References
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- Ahmed N., Dobrindt U., Hacker J., Hasnain S. E. 2008. Genomic fluidity and pathogenic bacteria: applications in diagnostics, epidemiology and intervention. Nat. Rev. Microbiol. 6:387–394 - PubMed
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