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. 2009:2009:bcr12.2008.1298.
doi: 10.1136/bcr.12.2008.1298. Epub 2009 May 21.

Unexpected finding on staging bone marrow aspirate for Hodgkin's lymphoma

Jens Samol  1 , Kelly J Susan
Affiliations

Unexpected finding on staging bone marrow aspirate for Hodgkin's lymphoma

Jens Samol et al. BMJ Case Rep. 2009.
No abstract available

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Figures

Figure 1
Figure 1
A. Chest x ray showing left mastectomy, azygos node and calcified opacity in left lower lobe. B. CT showing mediastinal lymphadenopathy. C. CT showing hepatosplenomegaly.
Figure 2
Figure 2
A. Immunohistochemical stain demonstrating CD15 positive Hodgkin/Reed–Sternberg (H-RS) cells. B. Immunohistochemical stain demonstrating CD30 positive H-RS cells.
Figure 3
Figure 3
Bone marrow aspirate at low power. Arrows show tumour cells.
Figure 4
Figure 4
A. Hodgkin cell at higher power. B. Same tumour cell at higher resolution demonstrating the nucleolus.
Figure 5
Figure 5
A. Hodgkin/Reed–Sternberg (H-RS) cell at high power resolution with surrounding cells representing reactive cells. B. Two further H-RS tumour cells at high power resolution also demonstrating multiple nucleoli.
See this image and copyright information in PMC

References

    1. Stein H. Hodgkin lymphoma. : Jaffe ES, Harries NL, Stein H, et al., eds. Pathology and genetics of tumours of haematopoietic and lymphoid tissues. Lyon, France: IACS Press, 2001: 237–53
    1. Canellos GP, Anderson JR, Propert KJ, et al. Chemotherapy of advanced Hodgkin’s disease with MOPP, ABVD, or MOPP alternating with ABVD. New Engl J Med 1992; 327: 1478–84 - PubMed
    1. CTCAE Version 3. http://ctep.cancer.gov (accessed 12 November 2008)

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