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. 2009:2009:bcr11.2008.1218.
doi: 10.1136/bcr.11.2008.1218. Epub 2009 May 8.

Pseudomembranous colitis in four patients with cystic fibrosis following lung transplantation

B Yates  1 , D M Murphy, A J Fisher, F K Gould, J L Lordan, J H Dark, P A Corris
Affiliations

Pseudomembranous colitis in four patients with cystic fibrosis following lung transplantation

B Yates et al. BMJ Case Rep. 2009.

Abstract

In the present study, 4 patients with cystic fibrosis undergoing lung transplantation (from a total of 137) who developed fulminant pseudomembranous colitis are described. Initial presentation was variable and the mortality rate was 50% despite urgent colectomy. In one case the presenting abdominal distension was thought to be due to meconium ileus equivalent. It is concluded that Clostridium difficile colitis may be a difficult diagnosis in patients with cystic fibrosis and follows a fulminant course after lung transplantation.

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Figures

Figure 1
Figure 1
CT scan of the abdomen showing gross thickening of the large bowel wall and obliteration of the lumen.
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