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. 2009:2009:bcr07.2008.0433.
doi: 10.1136/bcr.07.2008.0433. Epub 2009 Apr 14.

In-transit metastasis of the breast region from malignant melanoma of the trunk

Mehmet Uludag  1 , Bülent Citgez, Ozay Ozkaya, Damlanur Sakiz
Affiliations

In-transit metastasis of the breast region from malignant melanoma of the trunk

Mehmet Uludag et al. BMJ Case Rep. 2009.

Abstract

Extramammarian cancer metastases to the breast are rare. Melanoma is one of the malignancies that can metastasise to the breast. The distinction between a primary breast carcinoma and a metastatic neoplasm is crucial because surgical and therapeutic treatment options will vary accordingly. The present report concerns a case of breast metastasis from melanoma of the trunk. A 50-year-old man with a self-detected left breast lump who had previously undergone wide local excision and axillary dissection for melanoma was admitted to our department. Ultrasonography showed an 0.8 cm hypoechoic nodule with silent margins. The palpable mass was excised. Surgical pathology revealed metastatic melanoma.

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Figures

Figure 1
Figure 1
Hypoechoic nodule in the left breast by ultrasonography.
Figure 2
Figure 2
Malign tumour infiltration, which contained spindle cells with distinct pleomorphic cytoplasma in dermis (HEX100).
Figure 3
Figure 3
Tumour cells stained strongly for S-100 (+) in the immunohistochemical assay (HEX100).
See this image and copyright information in PMC

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