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. 2011:2011:841949.
doi: 10.4061/2011/841949. Epub 2011 May 12.

Thyroid antibodies and miscarriage: where are we at a generation later?

Alex Stagnaro-Green  1
Affiliations

Thyroid antibodies and miscarriage: where are we at a generation later?

Alex Stagnaro-Green. J Thyroid Res. 2011.

Abstract

In 1990, an association between thyroid antibody positivity and spontaneous miscarriage was first reported. A generation has passed since the initial observation. Over that time a robust literature has developed which has confirmed the initial finding and expanded upon it. The present paper reviews the literature that has been generated over the last twenty years on the following topics: (1) thyroid antibodies and spontaneous miscarriage, (2) thyroid antibodies and recurrent abortion, (3) etiology of pregnancy loss in thyroid antibody positive women, and (4) discussion of future research directions.

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Figures

Figure 1
Figure 1
Percentage of spontaneous miscarriage in unselected pregnancies in women who were thyroid antibody positive (TAb+) and thyroid antibody negative (TAB−).
Figure 2
Figure 2
Percentage of thyroid antibody positivity in women with recurrent abortion (Recurrent Ab) and controls.
See this image and copyright information in PMC

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