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Comparative Study
. 1990 Jun;109(6):548-50.

[Is xanthine oxidase a universal source of superoxide radicals in ischemic and reperfusion lesions?]

[Article in Russian]
Iu E Rashba, L G Nagler, L S Vartanian, L A Oktiabr'skaia, M V Bilenko
  • PMID: 2168771
Comparative Study

[Is xanthine oxidase a universal source of superoxide radicals in ischemic and reperfusion lesions?]

[Article in Russian]
Iu E Rashba et al. Biull Eksp Biol Med. 1990 Jun.

Abstract

While studying xanthine-xanthine oxidase system it was found, that a considerable accumulation of xanthine and uric acid occurred whereas xanthine dehydrogenase did not transfer in xanthine oxidase during 2 hours of total rat liver ischemia. These data make it possible to reject the generally accepted hypothesis of xanthine oxidase key role in free radical mechanism of ischemia damage.

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