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Review
. 2011 May;15(2):223-43, vii-x.
doi: 10.1016/j.cld.2011.03.006.

The global epidemiology of hepatocellular carcinoma: present and future

Katherine A McGlynn  1 , W Thomas London
Affiliations
Review

The global epidemiology of hepatocellular carcinoma: present and future

Katherine A McGlynn et al. Clin Liver Dis. 2011 May.

Abstract

The global risk of hepatocellular carcinoma (HCC) has been largely driven by hepatitis B virus (HBV) infection for the past century, along with hepatitis C virus (HCV), aflatoxin, excessive alcohol consumption, and obesity/diabetes. The dominant effect of HBV on global HCC risk should decline as the population vaccinated against HBV grows older. Infection with HCV is also expected to decline. Projections of HCV-related HCC rates remaining high for another 30 years may be overly pessimistic. Alcohol may be less of a factor in HCC in coming years. However, obesity and diabetes may become even more important risk factors for HCC.

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Figures

Figure 1
Figure 1
Age-adjusted incidence rates per 100,000 of liver cancer among males by region. Cancer Incidence in 5 Continents. Age adjusted to world standard.
Figure 2
Figure 2
Age-adjusted incidence rates per 100,000 of liver cancer among selected Chinese populations. Cancer Incidence in 5 Continents. Age adjusted to world standard.
Figure 3
Figure 3
Global prevalence of chronic infection with hepatitis B virus, 2006. Centers for Disease Control: http://wwwnc.cdc.gov/travel/yellowbook/2010/chapter-5/hepatitis-c.aspx
Figure 4
Figure 4
Global prevalence of hepatitis C infection. Centers for Disease Control: http://wwwnc.cdc.gov/travel/yellowbook/2010/chapter-5/hepatitis-c.aspx
See this image and copyright information in PMC

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