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Practice Guideline
. 2011 Aug;64(8):649-53.
doi: 10.1136/jcp.2011.089847. Epub 2011 Jun 20.

HER2 testing in the UK: recommendations for breast and gastric in-situ hybridisation methods

J M S Bartlett  1 , J Starczynski, Neil Atkey, E Kay, A O'Grady, Michael Gandy, Merdol Ibrahim, Bharat Jasani, I O Ellis, S E Pinder, R A Walker
Affiliations
Practice Guideline

HER2 testing in the UK: recommendations for breast and gastric in-situ hybridisation methods

J M S Bartlett et al. J Clin Pathol. 2011 Aug.

Abstract

These guidelines supplement existing guidelines on HER2 testing by immunohistochemistry and in-situ hybridisation(ISH) methods in the UK. They provide a specific focus on aspects of guidance relevant to HER2 ISH testing methods, both fluorescent and chromogenic. They are formulated to give advice on methodology, interpretation and quality control for ISH-based testing of HER2 status in common tumour types, including both breast and gastric tumours. The aim is to ensure that all ISH-based testing is accurate, reliable and timely.

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