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Case Reports
. 2011 Sep;30(9):1020-3.
doi: 10.1097/ICO.0b013e31820967bd.

Management and outcome of microbial anterior scleritis

Affiliations
Case Reports

Management and outcome of microbial anterior scleritis

Matthew A Cunningham et al. Cornea. 2011 Sep.

Abstract

Purpose: To evaluate the prevalence, predisposing factors, and outcomes of bacterial and fungal scleritis.

Methods: We reviewed the clinical findings, therapeutic interventions, and visual outcomes of patients with suppurative scleral inflammation without preceding microbial keratitis who had microorganisms isolated from scleral scrapings.

Design: Retrospective interventional case series.

Results: Of 349 patients with scleritis diagnosed from 1999 to 2009, 6 adults (1.7%) presented with suppurative inflammation of the anterior sclera due to Pseudomonas aeruginosa (2), Streptococcus pneumoniae (2), Staphylococcus aureus (1), and Scedosporium apiospermum/Pseudallescheria boydii (1). Each had ocular surgery of the affected eye before presentation. Intraocular extension occurred in 2 eyes. After local and systemic antimicrobial therapy, all improved without evisceration or enucleation, and 4 attained vision of 20/60 or better.

Conclusions: Bacterial or fungal scleritis is an uncommon ocular infection that can belatedly follow anterior segment procedures. Antimicrobial therapy and surgical intervention can successfully control progressive suppuration and reduce vision-limiting complications.

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Conflict of interest statement

The authors have no financial conflicts/proprietary interests in any products named in this article.

Figures

FIGURE 1
FIGURE 1
Case 2. Streptococcus pneumonia scleritis following pterygium surgery. A large scleral nasal abscess with associated purulent material noted centrally. After sclerectomy and drainage, subconjunctival, topical, and oral antibiotics there was complete resolution of the scleritis 14 days after initiation of treatment.
FIGURE 2
FIGURE 2
Case 3. Pseudomonas aeruginosa scleritis following pterygium surgery. A. Calcified scleral plaque with inflammation. B. After eight weeks of antibacterial therapy, scleral patch graft with rotating conjunctival flap was performed.

References

    1. Hemady R, Sainz de la Maza M, Raizman MB, et al. Six cases of scleritis associated with systemic infection. Am J Ophthalmol. 1992;114:55–62. - PubMed
    1. Ramesh S, Ramakrishnan R, Bharathi MJ, et al. Prevalence of bacterial pathogens causing ocular infections in South India. Indian J Pathol Microbiol. 2010;53:281–286. - PubMed
    1. Su CY, Tsai JJ, Chang YC, et al. Immunologic and clinical manifestations of infectious scleritis after pterygium excision. Cornea. 2006;25:663–666. - PubMed
    1. Moreno Honrado M, del Campo Z, Buil JA. A case of necrotizing scleritis resulting from Pseudomonas aeruginosa. Cornea. 2009;28:1065–1067. - PubMed
    1. Okhravi N, Odufuwa B, McCluskey P, et al. Scleritis. Surv Ophthalmol. 2005;50:351–363. - PubMed

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