Conjugated polymer nanoparticles for small interfering RNA delivery
- PMID: 21695337
- DOI: 10.1039/c1cc10991j
Conjugated polymer nanoparticles for small interfering RNA delivery
Abstract
Loosely aggregated conjugated polymer nanoparticles (CPNs) were used as nontoxic and efficient small interfering RNA (siRNA) delivery vehicles with delivery visualization. A significant down regulation (94%) of a target gene was achieved by transfection of HeLa cells with the CPNs/siRNA complexes, supporting CPN as a promising siRNA delivery carrier.
Publication types
MeSH terms
Substances
Grants and funding
LinkOut - more resources
Full Text Sources
Other Literature Sources
