Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1990;47(6):485-9.
doi: 10.1016/0024-3205(90)90607-s.

Fetal and maternal levels of corticosterone and ACTH after pharmacological adrenalectomy

T Z Baram  1 , L Schultz
Affiliations
Free article

Fetal and maternal levels of corticosterone and ACTH after pharmacological adrenalectomy

T Z Baram et al. Life Sci. 1990.
Free article

Erratum in

  • Life Sci 1990;47(12):1071

Abstract

A paradigm of pharmacological adrenalectomy of pregnant rats and fetuses in utero is described. A regimen of twice daily metyrapone injections (10 mg/100 gm body weight), results in marked depression of serum corticosterone in pregnant and in fetal rats without surgical trauma and stress. The technique should be useful in a wide variety of studies involving the developing brain-adrenal axis.

PubMed Disclaimer

Publication types