Establishment of a SV40-transformed cell line from primary culture of rat dorsolateral prostatic epithelial cells
- PMID: 2170156
- DOI: 10.1016/0014-4827(90)90196-h
Establishment of a SV40-transformed cell line from primary culture of rat dorsolateral prostatic epithelial cells
Abstract
A permanent cell line of the rat dorsolateral prostate epithelium was established after transformation of primary cultured cells with simian virus 40 (SV40). The established cells had SV40 T-antigen in their nuclei but lacked such typical characteristics of transformed cells as piled-up growth. They grew in a monolayer with an epithelial morphology, were stained with antikeratin antisera, and also retained an ability to form dome-like structure at a confluent state.
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