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Case Reports
. 2011 Mar:8 Suppl 2:314-21.

Papillary thyroid cancer in thalassaemia

Maria Rita Govoni  1 , Monica Sprocati, Elena Fabbri, Nicolò Zanforlin, Vincenzo De Sanctis
Affiliations
  • PMID: 21705985
Case Reports

Papillary thyroid cancer in thalassaemia

Maria Rita Govoni et al. Pediatr Endocrinol Rev. 2011 Mar.

Abstract

Thyroid cancer is the most frequent endocrine neoplasm in the general population. Its incidence is 5-10/100,000 per year, with an annual death rate of 0.2-1.2/100,000 in men and 0.4-2.8/100,000 in women. In thalassaemia patients the frequency of this disease is unknown. In this paper we describe five cases of papillary thyroid cancer in thalassaemia patients followed at the Day Hospital for Thalassaemia and Haemoglobinopathies, in Ferrara, Italy. We consider the possible key role of iron as a carcinogenic agent and we also discuss the practical implications of our clinical observations.

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