Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2012 Jan;463(1):23-30.
doi: 10.1007/s00424-011-0986-6. Epub 2011 Jun 28.

Circadian rhythms and sleep--the metabolic connection

Urs Albrecht  1
Affiliations
Review

Circadian rhythms and sleep--the metabolic connection

Urs Albrecht. Pflugers Arch. 2012 Jan.

Abstract

The circadian system coordinates mammalian physiology and behavior with the environmental light-dark cycle. It allocates sleep to the inactivity phase using various mechanisms involving neurotransmitters, nuclear receptors, and protein kinases. These pathways are related to metabolism, indicating that the circadian system and sleep are connected via metabolic parameters. This suggests that organs other than the brain may "sleep." A hypothetic view on this aspect is presented providing a different perspective on sleep regulation.

PubMed Disclaimer

References

    1. Cell. 2002 Jul 26;110(2):251-60 - PubMed
    1. Neuron. 2008 Mar 27;57(6):819-26 - PubMed
    1. J Neurochem. 2010 Jan;112(2):321-31 - PubMed
    1. Neurosci Lett. 2000 Jan 28;279(2):109-12 - PubMed
    1. Cold Spring Harb Symp Quant Biol. 2007;72:167-76 - PubMed

Publication types

LinkOut - more resources