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Review
. 2011 Jun;40(3):223-35.
doi: 10.1080/03079457.2011.566260.

Infectious bronchitis virus variants: a review of the history, current situation and control measures

J J Sjaak de Wit  1 , Jane K A Cook, Harold M J F van der Heijden
Affiliations
Review

Infectious bronchitis virus variants: a review of the history, current situation and control measures

J J Sjaak de Wit et al. Avian Pathol. 2011 Jun.

Abstract

The history, current situation and control measures for infectious bronchitis virus (IBV) variants are reviewed. A large number of IBV variants exist worldwide; some being unique to a particular area, others having a more general distribution. The possible reasons why some strains spread readily over major parts of the world, whereas other strains stay more localized are discussed. The advantages and disadvantages of strain classification by protectotyping, serotyping and genotyping are discussed in relation to in vivo protection. The different vaccination strategies are also considered.

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Figures

Figure 1.
Figure 1.. Phylogenetic tree for a selection of IBV variants from different parts of the world showing the wide diversity of IBV. The tree is based on comparison of the partial S gene (between nucleotides 20,447 and 20,924—numbering compared with the genome of Ark DPI; Ammayappan et al., 2008), coding for a part of the S1 glycoprotein including the highly variable regions 1 and 2. The phylogenetic tree analysis was conducted by neighbour-joining method using bootstrap analysis (100 replications).
Figure 2.
Figure 2.. Correlation between the level of homology in the S1 region of the S gene of IBV strains and the level of cross-protection between these strains as reported in seven publications.
Figure 3.
Figure 3.. Average level of homology between four strains of IBV in 160 different windows of 10 nucleotides of nucleotides 1 to 1600 of the S1 region on the S gene of different genotypes/serotypes (Adzhar et al., 1997).
Figure 4.
Figure 4.. Average level of homology between four strains of IBV in 16 different windows of 100 nucleotides of nucleotides 1 to 1600 of the S1 region on the S gene of different genotypes/serotypes (Adzhar et al., 1997).
Figure 5.
Figure 5.. Average level of homology between four strains of IBV in four different windows of 400 nucleotides of nucleotides 1 to 1600 of the S1 region on the S gene of different genotypes/serotypes (Adzhar et al., 1997).
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References

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