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. 2011 Jul-Aug;2(4):189-93.
doi: 10.4161/bbug.2.4.16961. Epub 2011 Jul 1.

E. coli O104:H4: social media and the characterization of an emerging pathogen

Pat G Casey  1 , Colin Hill, Cormac Gm Gahan
Affiliations

E. coli O104:H4: social media and the characterization of an emerging pathogen

Pat G Casey et al. Bioeng Bugs. 2011 Jul-Aug.

Abstract

The 2011 German E. coli O104:H4 outbreak resulted in thousands of cases of enterohaemorrhagic illness, with approximately 25% of these progressing to develop haemolytic uraemic syndrome (HUS). This high rate of progression to HUS was the first indicator that the bacterial cause of illness was not a typical enterohaemorrhagic E. coli (EHEC) strain. Collaborative bioinformatic analysis while the outbreak was still in progress indicated that the O104:H4 strain was in fact an enteroaggregative E. coli (EAEC) strain which had acquired genes for the production of Shiga - like toxin.

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