Review
doi: 10.1016/0014-5793(90)80436-m.
Pathobiochemistry of CO poisoning
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- PMID: 2172009
- DOI: 10.1016/0014-5793(90)80436-m
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Review
Pathobiochemistry of CO poisoning
FEBS Lett.
.
Free article
Abstract
A hypothesis for the pathobiochemical mechanism of CO poisoning, amenable to in vivo testing with optical reflectance spectrophotometry, is presented. It differs from the classical formulation in which loss of cytochrome c oxidase function is attributed entirely to O2 depletion, by including ligation and oxygenation of CO as essential components of the inhibitory process.
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