Warfarin-related nephropathy: another newly recognized complication of an old drug
- PMID: 21720303
- DOI: 10.1038/ki.2011.85
Warfarin-related nephropathy: another newly recognized complication of an old drug
Abstract
Since its approval in the 1950s, warfarin has been the most often prescribed anticoagulant, with attendant risks of bleeding. Brodsky et al. describe another potential complication of warfarin therapy. Warfarin-related nephropathy (WRN) has been described in patients with chronic kidney disease and appears to accelerate the rate of progression and increase the risk of death. The interactions between warfarin and chronic kidney disease are complex, and the recognition of the potential complications is expanding.
Comment on
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Warfarin-related nephropathy occurs in patients with and without chronic kidney disease and is associated with an increased mortality rate.Kidney Int. 2011 Jul;80(2):181-9. doi: 10.1038/ki.2011.44. Epub 2011 Mar 9. Kidney Int. 2011. PMID: 21389969 Free PMC article.
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