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Review
. 2011 Aug;63(8):640-7.
doi: 10.1002/iub.475. Epub 2011 Jun 30.

Dynamic factors controlling carrier anchoring on vascular cells

Affiliations
Review

Dynamic factors controlling carrier anchoring on vascular cells

Tirumani N Swaminathan et al. IUBMB Life. 2011 Aug.

Abstract

This article reviews experimental and modeling methods for determining the critical roles played by the various factors that control nanocarrier drug delivery to vascular endothelial cells.

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Figures

Figure 1
Figure 1
Schematic representation of nanoparticle segregation in smaller blood vessels.
Figure 2
Figure 2
Schematic illustration of factors influencing targeted nanocarrier capture by antigen expressing endothelial cell surfaces.
Figure 3
Figure 3
Cartoon depiction of flow-induced nanocarrier translational and rotational motion, antigen lateral diffusion within the cell membrane and antigen flexural movement.
Figure 4
Figure 4
Schematic representation of the Bell spring model for the interaction pair between an antibody and an antigen.
Figure 5
Figure 5
Passive tissue targeting in the blood vessels by nanoparticles.
Figure 6
Figure 6
Schematic representation of the drug release from the nanoparticles to the targeted site.

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