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Comment
. 2011 Jul;13(4):273-6.
doi: 10.2310/8000.2011.110243.

Steroids for patients in septic shock: the results of the CORTICUS trial

Alina Toma  1 , Angela Stone, Robert S Green, Sara Gray
Affiliations
Comment

Steroids for patients in septic shock: the results of the CORTICUS trial

Alina Toma et al. CJEM. 2011 Jul.

Abstract

Clinical question: What is the role of steroids in septic shock in the emergency department?

Article chosen: Sprung CL, Annane D, Keh D, et al; CORTICUS Study Group. Hydrocortisone therapy for patients with septic shock. N Engl J Med 2008;358:111-24.

Study objective: To assess the safety and efficacy of low-dose hydrocortisone therapy for patients with septic shock and to compare outcomes based on response to corticotropin testing.

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  • Hydrocortisone therapy for patients with septic shock.
    Sprung CL, Annane D, Keh D, Moreno R, Singer M, Freivogel K, Weiss YG, Benbenishty J, Kalenka A, Forst H, Laterre PF, Reinhart K, Cuthbertson BH, Payen D, Briegel J; CORTICUS Study Group. Sprung CL, et al. N Engl J Med. 2008 Jan 10;358(2):111-24. doi: 10.1056/NEJMoa071366. N Engl J Med. 2008. PMID: 18184957 Clinical Trial.