Islets have a lot of nerve! Or do they?
- PMID: 21723498
- PMCID: PMC3623930
- DOI: 10.1016/j.cmet.2011.06.004
Islets have a lot of nerve! Or do they?
Abstract
The autonomic nervous system influences insulin and glucagon secretion. In this issue, Rodriguez-Diaz et al. (2011) show that mouse and human islets differ in their innervation patterns, yet the effect of neural activation on islet hormone secretion is similar. Key questions raised by this species difference have potential relevance to diabetic therapeutics.
Copyright © 2011 Elsevier Inc. All rights reserved.
Comment on
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Innervation patterns of autonomic axons in the human endocrine pancreas.Cell Metab. 2011 Jul 6;14(1):45-54. doi: 10.1016/j.cmet.2011.05.008. Cell Metab. 2011. PMID: 21723503 Free PMC article.
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